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What is Mitosis?

In 1887, the German anatomy biologist, Water Fleming, coined the term mitosis which comes from the Greek language and equates to “wrap thread” from mitos and also “act or process” from the osis part of mitosis. This term was based on the warped thread appearance of the chromatin of the cell nucleus in the initially steras of mitosis. Now, what is mitosis as a process? Mitosis is the process in cell division whereby the nucleus of the cell divides (in a multiple phase), providing climb to 2 similar daughter cells.

You watching: Mitosis is done by your body cells. what types of cells do not undergo mitosis?

Mitosis happens in all eukaryotic cells (plants, pets, and fungi). It is the process of cell regeneration and development in a plant, animal or fungus. It is repeatedly occurring throughout our bodies; it is also happening while you are reading this. Cells repetitively die; this process is termed apoptosis (programmed cell death). For you to stay alive and fully practical, these cells must be consistently reinserted. Mitosis is essential to this process. Mitosis is the factor we have the right to prosper, heal wounds, and also relocation damaged cells.

Mitosis is additionally necessary in organisms which redevelop asexually: this is the only way that these cells deserve to redevelop. This is the one vital process that sustains populaces of asex-related organisms. Mitosis permits for some organisms to main alternating life stperiods (asex-related and sexual, such as fungi).

The crucial to mitosis developing is the existence of a nucleus. Because of this, organisms without nuclei (prokaryotes) miss out on out on this outstanding procedure.

Before Mitosis

Before mitosis starts, the chromosomes in the nucleus of the cell undergo replication. This is bereason mitosis produces 2 daughter cells similar to the parent cell; so the variety of chromosomes in the parent and also daughter cells need to be the exact same. Mitosis produces two diploid cells from one diploid cell. Thus, chromosome numbers should double before mitosis occurs. Keep in mind; diploid describes the variety of chromosomes in a cell: haploid cells have one collection of chromosomes (n), as is uncovered in a gamete (sex cell), whereas diploid cells have two sets of chromosomes (2n).

Summary of Mitosis

Throughout mitosis, all chromosomes separate right into chromatids (the two halves of a chromosome). These chromatids are then separated in space before cell department, to develop the chromatic makeup of each daughter cell. Because tright here are double the number of diploid chromosomes in the parent cell (2 X 2n = 4n), as soon as these chromosomes are separated right into their chromatids and also separation into two teams, each group will have the exact same variety of chromatids, and also therefore chromosomes, as each various other and as the parent cell. The complace of these chromosomes will certainly likewise be identical. Once the chromosomes are separated in space, cell division occurs to create two daughter cells. Hence, mitosis provides chromosome replication to produce 2 similar diploid daughter cells, which are genetically the same to the diploid parent cell. This method all your cells have identical DNA complace.

The Phases of Mitosis

The procedure of mitosis have the right to be mind boggling to master fully; here we will certainly try to work through it systematically. First off, mitosis can be split into 5 phases: Prophase, prometaphase, metaphase, anaphase and telophase. Some textbooks differ in the number of phases. In some instances they carry out away via prometaphase and also simply store the 4 standard phases.

What precisely happens in each phase of mitosis in pets might differ to what happens in plants. Nonethemuch less, all cells undergoing mitosis will certainly in one means or another undergo each of the above mentioned phases.

You will have to familiarize yourself with the adhering to terms to totally understand also the phases of mitosis described below:

Cell furrow/cleavage furrow
Image Source: Flickr
The indentation uncovered in the cell membrane of a newly split animal cell
Cell plateThe synthesized department of a plant cell lhelp across the metaphase plate. This later forms the middle lamella
CentrioleImage Source: Wikimedia CommonsAn organelle connected with spindle fiber production, situated in the centrosome. These are only discovered in pet cells
CentrosomeThe component of the cytoplasm which includes the centrioles


Hollow protein tubes which develop spindle fibers (among various other things)
Image Source: Wikimedia Commons
The protein which provides up microtubules
Kinetochore microtubules 

Image Source: Wikimedia Commons
The microtubules which connect the centrosome to the kinetochore
KinetochorePlates of protein at a chromosome’s centromere, to which spindle fibers connect in the time of mitosis
Image Source: Wikimedia Commons
The point of constriction of a chromosome
Image Source: Wikimedia Commons
The protein which binds two sister chromatids
Image Source: Wikimedia Commons
Division of the cytoplasm into 2 equal parts
Equatorial plane/metaphase plate
Image Source:
The midline of the cell along which chromosomes align during metaphase
Image Source: Wikimedia Commons
The duration in between mitosis occurrences; the duration in between one telophase and the next prophase
Middle lamella
Image Source: Wikimedia Commons
The cell framework in between nearby plant cell walls
Nuclear envelope 
Image Source: Wikimedia Commons
The double membrane which encloses the nucleus
NucleolusThe facility of rRNA production within the nucleus
Sister chromatids
Image Source: Wikimedia Commons
The two identical chromatids which develop a chromosome
Spindle fibersImage Source: Wikimedia CommonsA bundle of microtubules running from one pole of the cell to one more, alengthy which chromosomes move

Now that the meanings are out of the way let us acquire started on the nitty gritty of this procedure.

1. Prophase

This is the longest phase of mitosis. Many vital events take place in this phase, the centrioles migrate, the spindle fibers are arranged, the nuclear envelope disintegrates, the nucleolus additionally disintegprices, and the chromatin fibers conthick (Figure 1).

Figure 1: The significant events arising in the prophase stage Image Source: Wikimedia Commons

Prophase in animal cells starts through the migration of 2 pairs of centrioles from simply outside the nucleus, in the centrosome, to polar ends of the cell. Once at polar ends of the cell, the centrioles promote the activity of microtubules from the cytoplasm into the spindle fibers. Plant and fungi cells execute not have centrioles; therefore, they skip this step.

While this is occurring, the nuclear envelope and also nucleolus disincorporate, releasing the chromatin within. The chromatin condenses, and also chromosomes end up being visible. The two chromatids comprising each chromosome are identical and also are well-known as sister chromatids. These are held together by cohesin.

Think of this phase this way, eextremely part of the cell that is involved in mitosis changes to prepare for the full mitotic procedure. For example, at the finish of mitosis the daughter cells need equal quantities of similar DNA, so tbelow hregarding be a way of making certain that the appropriate contents go to the appropriate cell. In other words, tbelow has to be an insurance device for making sure that one cell does not end up through 2 copies of the one chromosome while the various other cell ends up with zero copies of this chromosome. This is completed via the difficult job-related of spindle fibers which pull the contents of the one daughter cell to the one side while the other “half” is pulled towards the opposite finish. This method, chromosomes never before get lost and go to the wrong finish. In short, points move to their rightful corners.

The visibility of the nuclear envelope borders just how far chromosomes, in particular, deserve to go. So prior to the cell deserve to consider pulling things apart and duplicating the contents, this obstacle should be removed someexactly how. This is why the nuclear envelope disintegprices.

If you follow the logic over it need to be evident why the various other events take place. Read over the explacountry presented below of the whole process and also then go.

2. Prometaphase

Prometaphase is an intermediary stage in between prophase and metaphase, below the cell is further all set for metaphase (figure 2).

Figure 2: The events of the prometaphase phase. Image Source: Wikimedia Commons

The spindle fibers affix to the kinetochore of each chromosome, at opposite sides of the centromere. Each sister chromatid is attached to its spindle fibers. These spindle fibers are consisted of of kinetochore microtubules. The chromosomes move to the equatorial airplane (or metaphase plate), which is perpendicular to the spindle fibers.

Here the exact same logic as over applies; it is all around making sure one chromatid ends up in one cell.

3. Metaphase

Metaphase refers to the alignment of the chromosomes at the equatorial plate following prometaphase.

Figure 3: The alignment of chromosomes at metaphase. Image Source: Wikimedia Commons

Each centromere is aligned through the equatorial plate while the chromosome arms extend towards the poles. Each sister chromatid (still joined at this point) is on a different side of the equatorial plate (number 3).

4. Anaphase

The Anaphase phase is the shortest phase of mitosis.

See more: nature ecology and evolution

Figure 4: Sister chromatids are pulled in the direction of opposite poles of the parent cell. Image Source: Wikimedia Commons

During this phase, disjunction occurs, and also migration of sister chromatids away from each various other to the poles of the cell occurs, resulting in the formation of daughter chromosomes.

Molecular electric motors use ATP to shorten the spindle fibers attached to each sister chromatid. In so doing, the chromosomes are break-up into 2 genetically similar sister chromatids, well-known as daughter chromosomes from this point. This event is recognized as disjunction. As the spindle fibers shorten better, the daughter chromosomes are attracted further apart till grouped at opposite ends of the cell.

Tright here is currently a diploid variety of chromosomes at each pole.

5. Telophase

Telophase is the last phase of mitosis. After anaphase, two diploid sets of chromosomes are located at each pole of the cell. Cytokinesis then occurs to split the cell right into two the same daughter cells.

Figure 5: The parental cell constricts to develop two daughter cells the same to each various other and also the parent cell. Image Source: Wikimedia Commons

In pet cells, the cytoplasm is constricted to the suggest that the cell is divided in two. This outcomes in a cell furrow. In plant cells, a cell plate is laid at the place of the equatorial airplane. This later on becomes the middle lamella of the plant cell.

Following this, chromosomes are packed to become chromatin, a nucleolus redevelops, and a nuclear envelope forms approximately the chromatin and also nucleolus. The spindle fibers disshow up, and the cell enters interphase.

Figure 6: A simplified overwatch of mitosis. Image Source: Wikimedia Commons

Now that we have explored all the different stages go back recheck out and also attempt to reason each occasion. This will carry out you through the ability to answer any kind of questions about each and also eincredibly one of these stperiods.

Why is Mitosis Important?

Mitosis is vital for three major reasons: development and also development cell replacement and also asexual remanufacturing.

1. Growth and also growth

After meiosis has produced a gamete, and also this has actually fsupplied with another gamete to form an embryo, the embryo grows utilizing mitosis. This growth proceeds throughout an organism’s life, in plants, animals, and fungi. In this means, the original chromosomal set is preserved.

2. Cell replacement

This occurs as soon as the original cell is damaged or wounded. New cells are created to replace those that were damaged. Instances of this are the healing of a cut or a broken bone. When old cells die, new ones relocation them to encertain continuing use.

3. Asex-related reproduction

Single-celled organisms and certain multicellular organisms use mitosis for asexual reproduction. This contains reproduction by fragmentation, as in the case of planaria, and reproduction by budding, as in the situation of sea anemones. Many kind of plants recreate using mitosis.

How is Mitosis Different from Meiosis?

First, we need to understand also what meiosis is. Meiosis is the replication of cells that outcomes in each daughter nucleus containing half of the parent cell’s chromosomes. Meiosis is supplied generally for the manufacturing of gametes, which are included in sex-related remanufacturing. Hence, the major distinction between mitosis and meiosis is that mitosis produces somatic (body) cells, which deserve to go on to end up being part of any kind of bodily tconcern, whereas meiosis only produces germ (sex) cells. Organisms which redevelop asexually cannot undergo meiosis, whereas all eukaryotic organisms undergo mitosis.

Mitosis and meiosis are comparable in that both can only happen in eukaryotic cells. This is because prokaryotic cells execute not contain a nucleus within which to begin the procedures of mitosis and also meiosis. Instead, prokaryotes replicate themselves utilizing binary fission. Both mitosis and meiosis start with DNA replication in the parent cell to create 4 sets of chromosomes: in mitosis, these sets are break-up to develop 2 diploid daughter cells, while in meiosis, these sets are separation to create 4 haploid daughter cells. This is bereason cells undergo just one division in mitosis, whereas they undergo 2 divisions in meiosis.

The table below summarizes the similarities and also differences in between mitosis and meiosis.




Can only take place in eukaryotes
DNA replication occurs first
Production of daughter cells based upon parent cell’s hereditary material
Means of cell replication in plants, pets, and fungi


Starts as diploid; ends as diploidStarts as diploid; ends as haploid
Used for growth/healing/asex-related reproductionUsed for sex-related reproduction
1 nuclear division2 nuclear divisions
5 phases8 phases
Daughter cell the same to parent cellDaughter cell not the same to parent cell
Results in 2 daughter cellsResults in 4 daughter cells
Produces somatic cellsProduces germ cells
Occurs in asex-related and sexual organismsOccurs only in sex-related organisms

Wrapping Up Biology and Mitosis

We now know that mitosis is the procedure of asex-related cell replication that is responsible for an organism’s advancement and growth, its cell replacement, and likewise, in certain organisms, asex-related remanufacturing. Mitosis is, therefore, an integral part of eukaryotic functioning. Mitosis differs from meiosis in that meiosis is the manufacturing of gametes, or sex cells, which will permit for genetic recombicountry in sexual organisms. However before, without mitosis, the embryos developed will never before thrive to end up being organisms. Mitosis is preyielded by DNA replication, to form 2 diploid sets of chromosomes. Mitosis has 5 phases. The initially phase is prophase, where the chromatic material is released from the nucleus, and also centromeres move to the poles of the cell. Prophase is adhered to by prometaphase, wbelow the chromosomes move to align at the equatorial aircraft of the cell. The third phase is metaphase, wright here the chromosomes are fully aligned at the equatorial airplane. Metaphase is adhered to by anaphase, wherein the sister chromatids developing each chromosome are pulled acomponent to assemble at the poles of the cell; and telophase, where cytokinesis develops two the same daughter cells, genetically the same to the parent cell. Following this, the cell enters interphase, the phase between mitosis occasions.

Mitosis has actually offered eukaryotic organisms the capability to regeneprice cells as essential without reducing the chromosome set while meiosis has actually enabled the possibility of genetic recombination. Both are important for the ubiquity and ongoing survival of eukaryotic organisms.

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