This computer animation demonstprices the steras of mitosis in an animal cell. Use the regulate buttons alengthy the bottom to run the complete animation. Click on any type of intermediate phase (for instance, Anaphase), and also see a representative still structure.

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Events in the time of Mitosis

Interphase: Cells may show up inactive during this phase, yet they are quite the opposite. This is the longest duration of the finish cell cycle throughout which DNA replicates, the centrioles divide, and proteins are proactively produced. For a complete description of the events in the time of Interphase, read around the Cell Cycle.

Prophase: During this first mitotic phase, the nucleolus fades and also chromatin (replicated DNA and linked proteins) condenses right into chromosomes. Each replicated chromosome comprises 2 chromatids, both via the same hereditary information. Microtubules of the cytoskeleton, responsible for cell shape, motility and also attachment to various other cells throughout interphase, disassemble. And the structure blocks of these microtubules are provided to thrive the mitotic spindle from the region of the centrosomes.

Prometaphase: In this stage the nuclear envelope breaks down so tbelow is no longer a recognizable nucleus. Some mitotic spindle fibers elongate from the centrosomes and also connect to kinetochores, protein bundles at the centromere area on the chromosomes wright here sister chromatids are joined. Other spindle fibers elongate however rather of attaching to chromosomes, overlap each other at the cell facility.

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Metaphase: Tension applied by the spindle fibers aligns all chromosomes in one aircraft at the facility of the cell.

Anaphase: Spindle fibers shorten, the kinetochores separate, and the chromatids (daughter chromosomes) are pulled acomponent and also start relocating to the cell poles.

Telophase: The daughter chromosomes arrive at the poles and also the spindle fibers that have actually pulled them apart disappear.

Cytokinesis: The spindle fibers not attached to chromosomes begin breaking dvery own until just that percent of overlap is left. It is in this area that a contractile ring cleaves the cell right into 2 daughter cells. Microtubules then reorganize right into a new cytoskeleton for the go back to interphase.

Cancer cells reproduce relatively easily in culture. In the Cancer Cell CAM compare the length of time these cells spend in interphase to that for mitosis to happen.